Compare Open Orchestra vs. TYPO3
Open Orchestra is an Open Source CMS built on the full stack framework. For database it uses a MongoDB, a NoSQL store rather than the more typical Relational Databases such as MySQL or PostgreSQL.
Typo3 is an established enterprise grade CMS built on PHP. In the past years they have struggled in their renewal project, but have since moved forward with Symfony components.
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CMSes vailable for comparison: BackBee, Bolt CMS, Concrete5, Contenta, Contentful, Cosmic.js, Craft CMS, Drupal 8, eZ Platform, Fork CMS, GraphCMS, Grav, Jarves, Joomla!, Kunstmaan, October CMS, Open Orchestra, Pagekit, Pimcore, PyroCMS 3, Reservoir, Spress, Sulu CMS, Symfony CMF, Symphony CMS